Synthesis and Antimicrobial Evaluation of Some Novel Trisubstituted s-Triazine Derivatives Based on Isatinimino, Sulphonamido, and Azacarbazole
Joint Authors
Dwivedi, Jaya
Sharma, Anamika
Jain, Sonika
Sharma, Swapnil
Kishore, D.
Agrawal, Meenakshi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
A study directed towards exploring the temperature-dependent reactivity of the chlorine atoms of 2,4,6-trichloro-s-triazine (TCT) in the nucleophilic displacement reaction, allowed a facile replacement of its chlorine atoms in succession with (i) N-amino methyl substituted isatin-3-hydrazones, (ii) N1-substituted-4-amino benzene sulphonamides, and (iii) 8-amino-4-oxo-N-benzyl-azacarbazole to produce the corresponding 2,4,6-trisubstituted-s-triazine, namely; 2-(N-amino methyl substituted isatin-3-hydrazinyl)-4-(N1-substituted-4′-amino benzenesulfonamidyl)-6-(8′-amino-4′-oxo-N-benzylazacarbazolyl)-1,3,5-triazine derivatives in acceptable yields.
The compounds prepared were further evaluated for their antibacterial activity against E.
coli and B.
subtilis and antifungal activities against A.
niger and A.
flavus, and some of them showed promising activity profile.
American Psychological Association (APA)
Jain, Sonika& Sharma, Anamika& Agrawal, Meenakshi& Sharma, Swapnil& Dwivedi, Jaya& Kishore, D.. 2012. Synthesis and Antimicrobial Evaluation of Some Novel Trisubstituted s-Triazine Derivatives Based on Isatinimino, Sulphonamido, and Azacarbazole. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-508595
Modern Language Association (MLA)
Jain, Sonika…[et al.]. Synthesis and Antimicrobial Evaluation of Some Novel Trisubstituted s-Triazine Derivatives Based on Isatinimino, Sulphonamido, and Azacarbazole. Journal of Chemistry No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-508595
American Medical Association (AMA)
Jain, Sonika& Sharma, Anamika& Agrawal, Meenakshi& Sharma, Swapnil& Dwivedi, Jaya& Kishore, D.. Synthesis and Antimicrobial Evaluation of Some Novel Trisubstituted s-Triazine Derivatives Based on Isatinimino, Sulphonamido, and Azacarbazole. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-508595
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508595