Effects of Oral, Vaginal, and Transdermal Hormonal Contraception on Serum Levels of Coenzyme Q10, Vitamin E, and Total Antioxidant Activity
Joint Authors
Palan, Prabhudas R.
Sadikovic, Azra
Mikhail, Magdy S.
Strube, Felix
Letko, Juraj
Source
Obstetrics and Gynecology International
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The use of the transdermal contraceptive patch is associated with greater bioavailability of ethinyl estradiol (EE) compared with contraceptive vaginal ring or oral contraceptives (OC).
We compared the influences of three contraceptive methods (OC, vaginal ring, and transdermal patch) on serum levels of coenzyme Q10, α-tocopherol, γ-tocopherol and total antioxidant capacity in premenopausal women.
Blood samples from 30 premenopausal women who used hormonal contraception for at least 4 months were collected.
Forty subjects who did not use any contraception were studied as control.
Serum levels of coenzyme Q10, α-tocopherol and γ-tocopherol were measured by high-pressure liquid chromatography.
Serum samples were also assayed for total antioxidant capacity (TAOC).
Serum levels of coenzyme Q10 and α-tocopherol were found to be significantly lower (P<.05) in all three contraceptive users compared with controls.
Contraceptive patch users had the lowest levels of coenzyme Q10 levels compared with normal subjects.
Serum TAOC levels were significantly lower (P<.05) among the contraceptive user groups.
Alterations in coenzyme Q10 and α-tocopherol induced by hormonal contraception and the potential effect(s) of exogenous ovarian hormones should be taken into consideration in future antioxidant research.
American Psychological Association (APA)
Palan, Prabhudas R.& Strube, Felix& Letko, Juraj& Sadikovic, Azra& Mikhail, Magdy S.. 2010. Effects of Oral, Vaginal, and Transdermal Hormonal Contraception on Serum Levels of Coenzyme Q10, Vitamin E, and Total Antioxidant Activity. Obstetrics and Gynecology International،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-508605
Modern Language Association (MLA)
Palan, Prabhudas R.…[et al.]. Effects of Oral, Vaginal, and Transdermal Hormonal Contraception on Serum Levels of Coenzyme Q10, Vitamin E, and Total Antioxidant Activity. Obstetrics and Gynecology International No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-508605
American Medical Association (AMA)
Palan, Prabhudas R.& Strube, Felix& Letko, Juraj& Sadikovic, Azra& Mikhail, Magdy S.. Effects of Oral, Vaginal, and Transdermal Hormonal Contraception on Serum Levels of Coenzyme Q10, Vitamin E, and Total Antioxidant Activity. Obstetrics and Gynecology International. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-508605
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508605