Adverse Prognostic Factors and Optimal Intervention Time for KyphoplastyVertebroplasty in Osteoporotic Fractures
Joint Authors
Filis, Andreas
Vrionis, Frank D.
Gerochristou, Maria A.
Aghayev, Kamran
Kokkalis, Zinon T.
Papanastassiou, Ioannis D.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
While evidence supports the efficacy of vertebral augmentation (kyphoplasty and vertebroplasty) for the treatment of osteoporotic fractures, randomized trials disputed the value of vertebroplasty.
The aim of this analysis is to determine the subset of patients that may not benefit from surgical intervention and find the optimal intervention time.
Methods.
27 prospective multiple-arm studies with cohorts of more than 20 patients were included in this meta-analysis.
We hereby report the results from the metaregression and subset analysis of those trials reporting on treatment of osteoporotic fractures with kyphoplasty and/or vertebroplasty.
Results.
Early intervention (first 7 weeks after fracture) yielded more pain relief.
However, spontaneous recovery was encountered in hyperacute fractures (less than 2 weeks old).
Patients suffering from thoracic fractures or severely deformed vertebrae tended to report inferior results.
We also attempted to formulate a treatment algorithm.
Conclusion.
Intervention in the hyperacute period should not be pursued, while augmentation after 7 weeks yields less consistent results.
In cases of thoracic fractures and significant vertebral collapse, surgeons or interventional radiologists may resort earlier to operation and be less conservative, although those parameters need to be addressed in future randomized trials.
American Psychological Association (APA)
Papanastassiou, Ioannis D.& Filis, Andreas& Aghayev, Kamran& Kokkalis, Zinon T.& Gerochristou, Maria A.& Vrionis, Frank D.. 2014. Adverse Prognostic Factors and Optimal Intervention Time for KyphoplastyVertebroplasty in Osteoporotic Fractures. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-508611
Modern Language Association (MLA)
Papanastassiou, Ioannis D.…[et al.]. Adverse Prognostic Factors and Optimal Intervention Time for KyphoplastyVertebroplasty in Osteoporotic Fractures. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-508611
American Medical Association (AMA)
Papanastassiou, Ioannis D.& Filis, Andreas& Aghayev, Kamran& Kokkalis, Zinon T.& Gerochristou, Maria A.& Vrionis, Frank D.. Adverse Prognostic Factors and Optimal Intervention Time for KyphoplastyVertebroplasty in Osteoporotic Fractures. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-508611
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508611