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Nutrition and Nonalcoholic Fatty Liver Disease : The Significance of Cholesterol
Joint Authors
Yasutake, Kenichiro
Nakamuta, Makoto
Enjoji, Munechika
Kohjima, Motoyuki
Source
International Journal of Hepatology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that ranges in severity from simple steatosis to cirrhosis.
NAFLD is considered to be associated with hepatic metabolic disorders, resulting in overaccumulation of fatty acids/triglycerides and cholesterol.
The pathogenesis and progression of NAFLD are generally explained by the “two-hit theory.” Most studies of lipid metabolism in the NAFLD liver have focused on the metabolism of fatty acids/triglycerides; therefore, the impact of cholesterol metabolism is still ambiguous.
In this paper, we review recent studies on NAFLD from the viewpoint of hepatic lipid metabolism-associated factors and discuss the impact of disordered cholesterol metabolism in the etiology of NAFLD.
The clinical significance of managing cholesterol metabolism, an option for the treatment of NAFLD, is also discussed.
American Psychological Association (APA)
Enjoji, Munechika& Yasutake, Kenichiro& Kohjima, Motoyuki& Nakamuta, Makoto. 2012. Nutrition and Nonalcoholic Fatty Liver Disease : The Significance of Cholesterol. International Journal of Hepatology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-508621
Modern Language Association (MLA)
Enjoji, Munechika…[et al.]. Nutrition and Nonalcoholic Fatty Liver Disease : The Significance of Cholesterol. International Journal of Hepatology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-508621
American Medical Association (AMA)
Enjoji, Munechika& Yasutake, Kenichiro& Kohjima, Motoyuki& Nakamuta, Makoto. Nutrition and Nonalcoholic Fatty Liver Disease : The Significance of Cholesterol. International Journal of Hepatology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-508621
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508621