A Review on JC Virus Infection in Kidney Transplant Recipients
Joint Authors
Ghio, Luciana
Ferraresso, Mariano
Belingheri, Mirco
Ferrante, Pasquale
Carluccio, Silvia
Edefonti, Alberto
Carloni, Camilla
Delbue, Serena
Source
Clinical and Developmental Immunology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The polyomavirus (PyV), JC virus (JCV), is a small nonenveloped DNA virus that asymptomatically infects about 80% of healthy adults and establishes latency in the kidney tissue.
In case of immunodeficient hosts, JCV can lytically infect the oligodendrocytes, causing a fatal demyelinating disease, known as progressive multifocal leukoencephalopathy (PML).
Although the reactivation of another human PyV, BK virus (BKV), is relatively common and its association with the polyomavirus associated nephropathy (PyVAN) following renal transplantation is proven, JCV replication and its impact on graft function and survival are less well studied.
Here we describe the biology of JCV and its pathological features and we review the literature regarding the JCV infection analyzed in the setting of transplantations.
American Psychological Association (APA)
Delbue, Serena& Ferraresso, Mariano& Ghio, Luciana& Carloni, Camilla& Carluccio, Silvia& Belingheri, Mirco…[et al.]. 2013. A Review on JC Virus Infection in Kidney Transplant Recipients. Clinical and Developmental Immunology،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-508683
Modern Language Association (MLA)
Delbue, Serena…[et al.]. A Review on JC Virus Infection in Kidney Transplant Recipients. Clinical and Developmental Immunology No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-508683
American Medical Association (AMA)
Delbue, Serena& Ferraresso, Mariano& Ghio, Luciana& Carloni, Camilla& Carluccio, Silvia& Belingheri, Mirco…[et al.]. A Review on JC Virus Infection in Kidney Transplant Recipients. Clinical and Developmental Immunology. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-508683
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508683