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Probiotic Potential of Lactobacillus Strains with Antimicrobial Activity against Some Human Pathogenic Strains
Joint Authors
Sieo, Chin Chin
Shokryazdan, Parisa
Faseleh Jahromi, Mohammad
Ho, Yin Wan
Alitheen, Noorjahan Banu
Liang, Juan Boo
Kalavathy, Ramasamy
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-03
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
The objective of this study was to isolate, identify, and characterize some lactic acid bacterial strains from human milk, infant feces, and fermented grapes and dates, as potential probiotics with antimicrobial activity against some human pathogenic strains.
One hundred and forty bacterial strains were isolated and, after initial identification and a preliminary screening for acid and bile tolerance, nine of the best isolates were selected and further identified using 16 S rRNA gene sequences.
The nine selected isolates were then characterized in vitro for their probiotic characteristics and their antimicrobial activities against some human pathogens.
Results showed that all nine isolates belonged to the genus Lactobacillus.
They were able to tolerate pH 3 for 3 h, 0.3% bile salts for 4 h, and 1.9 mg/mL pancreatic enzymes for 3 h.
They exhibited good ability to attach to intestinal epithelial cells and were not resistant to the tested antibiotics.
They also showed good antimicrobial activities against the tested pathogenic strains of humans, and most of them exhibited stronger antimicrobial activity than the reference strain L.
casei Shirota.
Thus, the nine Lactobacillus strains could be considered as potential antimicrobial probiotic strains against human pathogens and should be further studied for their human health benefits.
American Psychological Association (APA)
Shokryazdan, Parisa& Sieo, Chin Chin& Kalavathy, Ramasamy& Liang, Juan Boo& Alitheen, Noorjahan Banu& Faseleh Jahromi, Mohammad…[et al.]. 2014. Probiotic Potential of Lactobacillus Strains with Antimicrobial Activity against Some Human Pathogenic Strains. BioMed Research International،Vol. 2014, no. 2014, pp.1-16.
https://search.emarefa.net/detail/BIM-508758
Modern Language Association (MLA)
Shokryazdan, Parisa…[et al.]. Probiotic Potential of Lactobacillus Strains with Antimicrobial Activity against Some Human Pathogenic Strains. BioMed Research International No. 2014 (2014), pp.1-16.
https://search.emarefa.net/detail/BIM-508758
American Medical Association (AMA)
Shokryazdan, Parisa& Sieo, Chin Chin& Kalavathy, Ramasamy& Liang, Juan Boo& Alitheen, Noorjahan Banu& Faseleh Jahromi, Mohammad…[et al.]. Probiotic Potential of Lactobacillus Strains with Antimicrobial Activity against Some Human Pathogenic Strains. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-16.
https://search.emarefa.net/detail/BIM-508758
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508758