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Detection of the Hematopoietic Stem and Progenitor Cell Marker CD133 during Angiogenesis in Three-Dimensional Collagen Gel Culture
Joint Authors
Akita, Masumi
Komatsu, Kumiko
Fujita, Keiko
Matsumoto, Sachiko
Tanaka, Kayoko
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
We detected the hematopoietic stem and progenitor cell marker CD133 using immunogold labeling during angiogenesis in a three-dimensional collagen gel culture.
CD133-positive cells were present in capillary tubes newly formed from aortic explants in vitro.
The CD133-positive cell population had the capacity to form capillary tubes.
Lovastatin strongly inhibited cell migration from aortic explants and caused the degradation of the capillary tubes.
The present study provides insight into the function of CD133 during angiogenesis as well as an explanation for the antiangiogenic effect of statins.
American Psychological Association (APA)
Akita, Masumi& Tanaka, Kayoko& Matsumoto, Sachiko& Komatsu, Kumiko& Fujita, Keiko. 2013. Detection of the Hematopoietic Stem and Progenitor Cell Marker CD133 during Angiogenesis in Three-Dimensional Collagen Gel Culture. Stem Cells International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-508779
Modern Language Association (MLA)
Akita, Masumi…[et al.]. Detection of the Hematopoietic Stem and Progenitor Cell Marker CD133 during Angiogenesis in Three-Dimensional Collagen Gel Culture. Stem Cells International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-508779
American Medical Association (AMA)
Akita, Masumi& Tanaka, Kayoko& Matsumoto, Sachiko& Komatsu, Kumiko& Fujita, Keiko. Detection of the Hematopoietic Stem and Progenitor Cell Marker CD133 during Angiogenesis in Three-Dimensional Collagen Gel Culture. Stem Cells International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-508779
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508779