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Rheumatological Findings in Candidates for Valvular Heart Surgery
Joint Authors
Ali Hassan Sayegh, Sadegh
Naderi, Nafiseh
Mostafavi Pour Manshadi, Seyed Mohammad Yousof
Bagher, Owlia Mohammad
Mirhosseini, Seyed Jalil
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background and Objectives.
Valvular heart diseases are among the frequent causes of cardiac surgery.
Some patients have a well-known rheumatic condition.
Heart valves are fragile connective tissues which are vulnerable to any systemic autoimmune diseases.
This study was designed to evaluate the frequency of rheumatological background in patients candidate for valvular heart surgery in Afshar Cardiovascular Center, Yazd, Iran.
Methods.
One hundred and twenty (120) patients candidate for valvular heart surgery were selected for this study.
Careful history and physical examination were undertaken from rheumatological stand points.
The most sensitive screening serologic tests were also assayed.
Results.
The result of this study showed that 53.3% were male and 46.6% were female with mean age of 48.18±17.65 years old.
45.8% of the patients had history of nonmechanical joint disease, 14.2% had history of rheumatological conditions in their family, and 30% had history of constitutional symptoms.
29.8% had positive joint dysfunction findings in their physical examination while 25.8% had anemia of chronic disease.
Positive Rheumatoid factor (RF), anticyclic citrullinated peptide (CCP, ACPA), C-reactive protein (CRP), antinuclear antibody (ANA), abnormal urine and elevated erythrocyte sedimentation rate (ESR) were 34, 2.5, 26.7, 4.2, 5, and 36.7%, respectively.
Antineutrophil cytoplasmic antibody (ANCA) and antiphospholipid (APL) were positive in a few cases.
Conclusion.
The findings of this study show immunologic bases for most patients with valvular heart diseases candidate for surgery.
Undifferentiated connective tissue diseases may play an important role in the pathophysiology of valvular damage.
American Psychological Association (APA)
Bagher, Owlia Mohammad& Mirhosseini, Seyed Jalil& Naderi, Nafiseh& Mostafavi Pour Manshadi, Seyed Mohammad Yousof& Ali Hassan Sayegh, Sadegh. 2012. Rheumatological Findings in Candidates for Valvular Heart Surgery. ISRN Rheumatology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-508832
Modern Language Association (MLA)
Bagher, Owlia Mohammad…[et al.]. Rheumatological Findings in Candidates for Valvular Heart Surgery. ISRN Rheumatology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-508832
American Medical Association (AMA)
Bagher, Owlia Mohammad& Mirhosseini, Seyed Jalil& Naderi, Nafiseh& Mostafavi Pour Manshadi, Seyed Mohammad Yousof& Ali Hassan Sayegh, Sadegh. Rheumatological Findings in Candidates for Valvular Heart Surgery. ISRN Rheumatology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-508832
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508832