Tc99m-DTPA Study to Validate an Experimental Model of Ureteral Obstruction in Rabbits : Preliminary Results
Joint Authors
Ramos, Celso Darío
Moro, Juliano César
Lima, Marcelo Lopes de
Coltro Neto, Fábio
Fregonesi, Adriano
Lima, Mariana da Cunha Lopes de
Miyaoka, Ricardo
Bertti, Rodolfo
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-29
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To create a ureteral obstruction experimental model that can be proved through Tc99m-DTPA renal scintigraphy and histopathological studies, without causing total renal function loss.
Materials and Methods.
Ten New Zealand white rabbits were submitted to a surgical experiment to create a model of unilateral obstruction to urinary flow.
Surgery procedure provided unilateral ureteral obstruction (left kidney) to urinary flow and posteriorly was evaluated by Tc99m-DTPA renal scintigraphy and histopathological study.
Tc99m-DTPA renal study was performed to detect and quantify signs of obstruction and to evaluate renal function.
Statistical analysis was performed through the Student t-test with a significance level of P<0.05.
Results.
Nine of the ten rabbits presented left renal unit obstruction and one nonobstructive on the Tc99m-DTPA and histopathological studies.
All the right renal units, which were not submitted to surgical procedure, were nonobstructed by the studies.
There was a general agreement between scintigraphy and histopathological results in both groups.
Conclusion.
The experimental model promoted the creation of ureteral obstruction in rabbits, confirmed by nuclear medicine scintigraphy and histopathology, and could be used in further studies to better understand urinary obstruction.
American Psychological Association (APA)
Lima, Marcelo Lopes de& Bertti, Rodolfo& Moro, Juliano César& Coltro Neto, Fábio& Miyaoka, Ricardo& Fregonesi, Adriano…[et al.]. 2013. Tc99m-DTPA Study to Validate an Experimental Model of Ureteral Obstruction in Rabbits : Preliminary Results. Advances in Urology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-508999
Modern Language Association (MLA)
Lima, Marcelo Lopes de…[et al.]. Tc99m-DTPA Study to Validate an Experimental Model of Ureteral Obstruction in Rabbits : Preliminary Results. Advances in Urology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-508999
American Medical Association (AMA)
Lima, Marcelo Lopes de& Bertti, Rodolfo& Moro, Juliano César& Coltro Neto, Fábio& Miyaoka, Ricardo& Fregonesi, Adriano…[et al.]. Tc99m-DTPA Study to Validate an Experimental Model of Ureteral Obstruction in Rabbits : Preliminary Results. Advances in Urology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-508999
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508999