Lipids and All-Cause Mortality among Older Adults : A 12-Year Follow-Up Study

Abstract EN

This is a 12-year follow-up cohort study with 800 people (60–85 years old).

The association between lipid disorders and mortality was analysed by Cox proportional hazard adjusted model.

All-cause mortality was considered the dependent variable, and lipid disorders as independent variables: total cholesterol (TC) >200 and <170 mg/dl, HDL-c <35 and 40, LDL-c >100 and 130, and triglycerides (TG) >50.

An initial analysis of all subjects was performed and a second was carried out after having excluded individuals with a body mass index (BMI) <20 kg/m2 or mortality in ≤2 years.

The mortality showed a positive association with low TC and a negative association with high TC and high LDL-c.

After the exclusion of underweight and premature mortality, there was a positive association only with TC <170 mg/dl (HR = 1.36, CI95%: 1.02–1.82).

The data did not show a higher risk with high levels of TC, LDL-c, and TG.

However, they showed higher mortality among older adults with low TC.