Glycogen as a Putative Target for Diagnosis and Therapy in Brain Pathologies
Joint Authors
Cloix, Jean-François
Hévor, Tobias
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-04
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Brain glycogen, a glucose polymer, is now considered as a functional energy store to the brain.
Indeed, when neurons outpace their own possibilities to provide themselves with energy, astrocytic metabolism is in charge of feeding neurons, since brain glycogen synthesis is mainly due to astrocyte.
Therefore, malfunctions or perturbations of astrocytic glycogen content, synthesis, or mobilization may be involved in processes of brain pathologies.
This is the case, for example, in epilepsies and gliomas, two different situations in which, brain needs high level of energy during acute or chronic conditions.
The purpose of the present paper is to demonstrate how brain glycogen might be relevant in these two pathologies and to pinpoint the possibilities of considering glycogen as a tool for diagnostic and therapeutic approaches in brain pathologies.
American Psychological Association (APA)
Cloix, Jean-François& Hévor, Tobias. 2011. Glycogen as a Putative Target for Diagnosis and Therapy in Brain Pathologies. ISRN Pathology،Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-509092
Modern Language Association (MLA)
Cloix, Jean-François& Hévor, Tobias. Glycogen as a Putative Target for Diagnosis and Therapy in Brain Pathologies. ISRN Pathology No. 2011 (2011), pp.1-17.
https://search.emarefa.net/detail/BIM-509092
American Medical Association (AMA)
Cloix, Jean-François& Hévor, Tobias. Glycogen as a Putative Target for Diagnosis and Therapy in Brain Pathologies. ISRN Pathology. 2011. Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-509092
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509092