A Coarse-Grained Molecular Dynamics Study of DLPC, DMPC, DPPC, and DSPC Mixtures in Aqueous Solution
Joint Authors
Basri, Mahiran
Abedi Karjiban, Roghayeh
Shaari, Nurul Syahidah
Gunasakaran, Uma Villashini
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The structural and dynamics properties of the bilayer comprising 128 molecules of dipalmitoylphosphatidylcholine (DPPC), dilauroylphosphatidylcholine (DLPC), dimyristoylphosphatidylcholine (DMPC), and distearoylphosphatidylcholine (DSPC) in water were investigated using a coarse-grained molecular dynamics (CG-MD) simulation technique.
The model mixture system was simulated at 298 K under semi-isotropic pressure conditions.
The aggregation was initiated from the random configurations followed by the formation of a bilayer over a period of 500 ns.
The calculated values of the area per lipid, thickness, and lateral diffusion for the mixed model were different from when a single lipid was used.
Our results confirmed that the chain length of the lipid molecules strongly affects the phospholipid bilayer’s physical properties.
American Psychological Association (APA)
Abedi Karjiban, Roghayeh& Shaari, Nurul Syahidah& Gunasakaran, Uma Villashini& Basri, Mahiran. 2013. A Coarse-Grained Molecular Dynamics Study of DLPC, DMPC, DPPC, and DSPC Mixtures in Aqueous Solution. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-509128
Modern Language Association (MLA)
Abedi Karjiban, Roghayeh…[et al.]. A Coarse-Grained Molecular Dynamics Study of DLPC, DMPC, DPPC, and DSPC Mixtures in Aqueous Solution. Journal of Chemistry No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-509128
American Medical Association (AMA)
Abedi Karjiban, Roghayeh& Shaari, Nurul Syahidah& Gunasakaran, Uma Villashini& Basri, Mahiran. A Coarse-Grained Molecular Dynamics Study of DLPC, DMPC, DPPC, and DSPC Mixtures in Aqueous Solution. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-509128
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509128