Is Contrast Medium Osmolality a Causal Factor for Contrast-Induced Nephropathy?
Joint Authors
De Cecco, Carlo N.
Meinel, Felix G.
Krazinski, Aleksander W.
Schoepf, U. Joseph
Vogl, Thomas J.
Bucher, Judith
Wang, Rui
Katzberg, Richard W.
McQuiston, Andrew D.
Bucher, Andreas M.
Spearman, James V.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The exact pathophysiology of contrast-induced nephropathy (CIN) is not fully clarified, yet the osmotic characteristics of contrast media (CM) have been a significant focus in many investigations of CIN.
Osmotic effects of CM specific to the kidney include transient decreases in blood flow, filtration fraction, and glomerular filtration rate.
Potentially significant secondary effects include an osmotically induced diuresis with a concomitant dehydrating effect.
Clinical experiences that have compared the occurrence of CIN between the various classes of CM based on osmolality have suggested a much less than anticipated advantage, if any, with a lower osmolality.
Recent animal experiments actually suggest that induction of a mild osmotic diuresis in association with iso-osmolar agents tends to offset potentially deleterious renal effects of high viscosity-mediated intratubular CM stagnation.
American Psychological Association (APA)
Bucher, Andreas M.& De Cecco, Carlo N.& Schoepf, U. Joseph& Meinel, Felix G.& Krazinski, Aleksander W.& Spearman, James V.…[et al.]. 2014. Is Contrast Medium Osmolality a Causal Factor for Contrast-Induced Nephropathy?. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-509162
Modern Language Association (MLA)
Bucher, Andreas M.…[et al.]. Is Contrast Medium Osmolality a Causal Factor for Contrast-Induced Nephropathy?. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-509162
American Medical Association (AMA)
Bucher, Andreas M.& De Cecco, Carlo N.& Schoepf, U. Joseph& Meinel, Felix G.& Krazinski, Aleksander W.& Spearman, James V.…[et al.]. Is Contrast Medium Osmolality a Causal Factor for Contrast-Induced Nephropathy?. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-509162
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509162