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Chloride Balance in Preterm Infants during the First Week of Life
Joint Authors
Kermorvant-Duchemin, Elsa
Bonsante, Francesco
Iacobelli, Silvia
Lapillonne, Alexandre
Gouyon, Jean-Bernard
Source
International Journal of Pediatrics
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To describe the chloride balance in infants born 25–32-week gestation, analyze the association of chloride changes with hydroelectrolytic status and their relationship with perinatal conditions, morbidities, and neurological outcome.
Methods.
For 7 days after birth, sodium and chloride balance, plasma potassium, phosphate, and total carbon dioxide (tCO2) were prospectively determined and strong ion difference (SID) calculated.
Three multivariate regression analyses were performed to identify factors associated with high plasma chloride concentration, low SID, and low tCO2.
Results.
107 infants were studied.
Plasma chloride concentration was significantly positively associated with plasma sodium concentration.
Higher plasma chloride and lower SID were significantly associated with lower plasma tCO2.
Chloride intake was the main independent factor associated with high plasma chloride, low SID, and low plasma tCO2, with lesser contribution of sodium intake and low gestational age (GA).
Also, patent ductus arteriosus and birth weight loss were independent factors affecting plasma chloride and SID.
Neither high chloride levels nor low SID were associated to impaired neurological outcome.
Conclusions.
In preterm infants, chloride balance is influenced by GA and by interrelationship between sodium and chloride intake.
High chloride levels are associated with metabolic acidosis but not related to increased risk of impaired neurological outcome.
American Psychological Association (APA)
Iacobelli, Silvia& Kermorvant-Duchemin, Elsa& Bonsante, Francesco& Lapillonne, Alexandre& Gouyon, Jean-Bernard. 2012. Chloride Balance in Preterm Infants during the First Week of Life. International Journal of Pediatrics،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-509183
Modern Language Association (MLA)
Iacobelli, Silvia…[et al.]. Chloride Balance in Preterm Infants during the First Week of Life. International Journal of Pediatrics No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-509183
American Medical Association (AMA)
Iacobelli, Silvia& Kermorvant-Duchemin, Elsa& Bonsante, Francesco& Lapillonne, Alexandre& Gouyon, Jean-Bernard. Chloride Balance in Preterm Infants during the First Week of Life. International Journal of Pediatrics. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-509183
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509183