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Forms, Crosstalks, and the Role of Phospholipid Biosynthesis in Autophagy
Joint Authors
Pereira, Leanne
Girardi, John Paul
Bakovic, Marica
Source
International Journal of Cell Biology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-16
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Autophagy is a highly conserved cellular process occurring during periods of stress to ensure a cell's survival by recycling cytosolic constituents and making products that can be used in energy generation and other essential processes.
Three major forms of autophagy exist according to the specific mechanism through which cytoplasmic material is transported to a lysosome.
Chaperone-mediated autophagy is a highly selective form of autophagy that delivers specific proteins for lysosomal degradation.
Microautophagy is a less selective form of autophagy that occurs through lysosomal membrane invaginations, forming tubes and directly engulfing cytoplasm.
Finally, macroautophagy involves formation of new membrane bilayers (autophagosomes) that engulf cytosolic material and deliver it to lysosomes.
This review provides new insights on the crosstalks between different forms of autophagy and the significance of bilayer-forming phospholipid synthesis in autophagosomal membrane formation.
American Psychological Association (APA)
Pereira, Leanne& Girardi, John Paul& Bakovic, Marica. 2012. Forms, Crosstalks, and the Role of Phospholipid Biosynthesis in Autophagy. International Journal of Cell Biology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-509216
Modern Language Association (MLA)
Pereira, Leanne…[et al.]. Forms, Crosstalks, and the Role of Phospholipid Biosynthesis in Autophagy. International Journal of Cell Biology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-509216
American Medical Association (AMA)
Pereira, Leanne& Girardi, John Paul& Bakovic, Marica. Forms, Crosstalks, and the Role of Phospholipid Biosynthesis in Autophagy. International Journal of Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-509216
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509216