Proinflammatory Effects of C-Peptide in Different Tissues
Joint Authors
Source
International Journal of Inflammation
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Atherosclerosis is well known as an inflammatory disease that can lead to clinical complications such as heart attack or stroke.
C-peptide as a cleavage product of proinsulin is in the last few decades known as an active peptide with a number of different effects on microvascular and macrovascular complications in type 2 diabetic patients.
Patients with insulin resistance and early type 2 diabetes show elevated levels of C-peptide in blood.
Several last findings demonstrated deposition of C-peptide in the vessel wall in ApoE-deficient mice and induction of local inflammation.
Besides that, C-peptide has proliferative effects on human mesangial cells.
This review discusses recently published proinflammatory effects of C-peptide in different tissues.
American Psychological Association (APA)
Vasic, Dusica& Walcher, Daniel. 2012. Proinflammatory Effects of C-Peptide in Different Tissues. International Journal of Inflammation،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-509309
Modern Language Association (MLA)
Vasic, Dusica& Walcher, Daniel. Proinflammatory Effects of C-Peptide in Different Tissues. International Journal of Inflammation No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-509309
American Medical Association (AMA)
Vasic, Dusica& Walcher, Daniel. Proinflammatory Effects of C-Peptide in Different Tissues. International Journal of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-509309
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509309