A Case Report of a Malignant Peripheral Nerve Sheath Tumor of the Oral Cavity in Neurofibromatosis Type 1
Joint Authors
Source
Case Reports in Otolaryngology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-06
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Patients with neurofibromatosis type 1 develop both benign and malignant tumors at an increased frequency.
Most of the malignant peripheral nerve sheath tumors (MPNSTs) are considered as high-grade sarcomas originating from tissues of mesenchymal origin.
It is generally accepted that MPNSTs occur in about 2% to 5% of neurofibromatosis patients.
In this paper, we present a 16-year-old male patient with neurofibromatosis who developed MPNST of the retromolar area.
The mass enlarged rapidly in a period of 6 weeks.
The patient was treated surgically, and a tumor mass with a diameter of 7×6×4 cm was excised, but after 8 months a recurrence was observed at the same site.
The sarcomatous change in a neurofibroma has an extremely poor prognosis, so patients with neurofibromatosis should be closely monitored for a possible malignancy.
A rapid change in size of a preexisting neurofibroma, infiltration of the adjacent structures, intralesional hemorrhage, and pain indicate a possible malignant transformation to MPNST.
American Psychological Association (APA)
Öztürk, Özmen& Tutkun, Alper. 2012. A Case Report of a Malignant Peripheral Nerve Sheath Tumor of the Oral Cavity in Neurofibromatosis Type 1. Case Reports in Otolaryngology،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-509595
Modern Language Association (MLA)
Öztürk, Özmen& Tutkun, Alper. A Case Report of a Malignant Peripheral Nerve Sheath Tumor of the Oral Cavity in Neurofibromatosis Type 1. Case Reports in Otolaryngology No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-509595
American Medical Association (AMA)
Öztürk, Özmen& Tutkun, Alper. A Case Report of a Malignant Peripheral Nerve Sheath Tumor of the Oral Cavity in Neurofibromatosis Type 1. Case Reports in Otolaryngology. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-509595
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509595