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Manufacturing Strategy for Multiwalled Carbon Nanotubes as a Biocompatible and Innovative Material
Joint Authors
Shimizu, Masayuki
Okamoto, Masanori
Usui, Yuki
Kato, Hiroyuki
Matsuda, Yoshikazu
Hara, Kazuo
Nakamura, Koichi
Ogihara, Nobuhide
Tsukahara, Tamotsu
Takanashi, Seiji
Aoki, Kaoru
Haniu, Hisao
Ishigaki, Norio
Saito, Naoto
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Abstract EN
We investigated the relationship between differences in multiwalled carbon nanotubes (MWCNTs) and the biological responses they elicit in order to develop biocompatible MWCNTs.
We exposed human bronchial epithelial (BEAS-2B) cells to two sizes and six grades of MWCNTs and measured the resulting cell viability, total reactive oxygen and/or nitrogen species (tROS/RNS) production, and cytokine secretion.
Although differences in cellular tROS production were associated with differences in grades of MWCNTs, the graphitization temperature of MWCNTs apparently did not influence tROS production.
However, cell viability was affected by MWCNT graphitization temperature and diameter.
Moreover, cytokine secretion was apparently affected by treatment temperature, but not MWCNT diameter.
We concluded that the highest temperature resulted in the most biocompatibility because impurities and carbon defects were removed from the MWCNTs.
However, other mechanisms are possible.
Therefore, it is important to optimize each type of MWCNT by monitoring biological responses that type elicits during the manufacturing stage for applications involving biology and medicine.
American Psychological Association (APA)
Haniu, Hisao& Saito, Naoto& Matsuda, Yoshikazu& Usui, Yuki& Aoki, Kaoru& Shimizu, Masayuki…[et al.]. 2011. Manufacturing Strategy for Multiwalled Carbon Nanotubes as a Biocompatible and Innovative Material. Journal of Nanotechnology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-509694
Modern Language Association (MLA)
Haniu, Hisao…[et al.]. Manufacturing Strategy for Multiwalled Carbon Nanotubes as a Biocompatible and Innovative Material. Journal of Nanotechnology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-509694
American Medical Association (AMA)
Haniu, Hisao& Saito, Naoto& Matsuda, Yoshikazu& Usui, Yuki& Aoki, Kaoru& Shimizu, Masayuki…[et al.]. Manufacturing Strategy for Multiwalled Carbon Nanotubes as a Biocompatible and Innovative Material. Journal of Nanotechnology. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-509694
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509694