Elevated Adiponectin Serum Levels in Women with Systemic Autoimmune Diseases
Joint Authors
Saas, Philippe
Dumoulin, Gilles
Gaugler, Beatrice
Toussirot, Éric
Bouhaddi, Malika
Nguyen, Nhu Uyen
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Adipose tissue produces a wide range of proteins that may influence the immune system.
In this study, we assessed the serum levels of leptin, adiponectin, and ghrelin, in association with the measurements of body composition, in 15 female patients with various autoimmune diseases (systemic lupus erythematosus, primary Sjögren's syndrome, sarcoidosis, mixed connective tissue disease, vasculitis, CREST syndrome, and polymyositis) and in 15 healthy female controls.
There were no statistically significant differences between the patients and controls with regard to serum leptin, serum ghrelin, global fat mass, adiposity, and fat mass in the android or gynoid regions, whereas serum adiponectin levels were higher in patients than controls (16.3±1.6 μg/mL versus 9.7±0.6 μg/mL; P=.01).
As adiponectin is known to exhibit potent anti-inflammatory properties, a high adiponectinemia in patients with systemic autoimmune disease may mitigate the inflammatory response.
However, the precise consequences of these elevated serum adiponectin levels on the metabolic syndrome development and atherosclerotic cardiovascular risk in this patient population still needs to be determined.
American Psychological Association (APA)
Toussirot, Éric& Gaugler, Beatrice& Bouhaddi, Malika& Nguyen, Nhu Uyen& Saas, Philippe& Dumoulin, Gilles. 2010. Elevated Adiponectin Serum Levels in Women with Systemic Autoimmune Diseases. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-509754
Modern Language Association (MLA)
Toussirot, Éric…[et al.]. Elevated Adiponectin Serum Levels in Women with Systemic Autoimmune Diseases. Mediators of Inflammation No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-509754
American Medical Association (AMA)
Toussirot, Éric& Gaugler, Beatrice& Bouhaddi, Malika& Nguyen, Nhu Uyen& Saas, Philippe& Dumoulin, Gilles. Elevated Adiponectin Serum Levels in Women with Systemic Autoimmune Diseases. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-509754
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509754