Assessment of the Variation Associated with Repeated Measurement of Gastrointestinal Transit Times and Assessment of the Effect of Oral Ranitidine on Gastrointestinal Transit Times Using a Wireless Motility Capsule System in Dogs
Joint Authors
Ivanek, Renata
Lidbury, Jonathan A.
Steiner, Jörg M.
Suchodolski, Jan S.
Source
Veterinary Medicine International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This study aimed to evaluate the variation associated with repeated measurement of gastrointestinal (GI) transit times and the effect of oral ranitidine on GI transit times in healthy dogs using a wireless motility capsule (WMC) system.
Eight privately owned healthy adult dogs were enrolled, and one developed diarrhea and was removed from the study.
For the first 3 repetitions, each dog was fed a standard meal followed by oral administration of a WMC.
For the 4th repetition, each dog was given ranitidine hydrochloride (75 mg PO every 12 hours) prior to and during assessment of GI transit times.
Mean between-subject coefficients of variation for gastric emptying time (GET), small and large bowel transit time (SLBTT), and total transit time (TTT) were 26.9%, 32.3%, and 19.6%, respectively.
Mean within-subject coefficients of variation for GET, SLBTT, and TTT were 9.3%, 19.6%, and 15.9%, respectively.
Median GET, SLBTT, and TTT without ranitidine were 719, 1,636, and 2,735 minutes, respectively.
Median GET, SLBTT, and TTT with ranitidine were 757, 1,227, and 2,083 minutes, respectively.
No significant differences in GI transit times were found between any of the 4 repetitions.
Under these experimental conditions, no significant effects of oral ranitidine on GI transit times were observed.
American Psychological Association (APA)
Lidbury, Jonathan A.& Suchodolski, Jan S.& Ivanek, Renata& Steiner, Jörg M.. 2012. Assessment of the Variation Associated with Repeated Measurement of Gastrointestinal Transit Times and Assessment of the Effect of Oral Ranitidine on Gastrointestinal Transit Times Using a Wireless Motility Capsule System in Dogs. Veterinary Medicine International،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-509755
Modern Language Association (MLA)
Lidbury, Jonathan A.…[et al.]. Assessment of the Variation Associated with Repeated Measurement of Gastrointestinal Transit Times and Assessment of the Effect of Oral Ranitidine on Gastrointestinal Transit Times Using a Wireless Motility Capsule System in Dogs. Veterinary Medicine International No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-509755
American Medical Association (AMA)
Lidbury, Jonathan A.& Suchodolski, Jan S.& Ivanek, Renata& Steiner, Jörg M.. Assessment of the Variation Associated with Repeated Measurement of Gastrointestinal Transit Times and Assessment of the Effect of Oral Ranitidine on Gastrointestinal Transit Times Using a Wireless Motility Capsule System in Dogs. Veterinary Medicine International. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-509755
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509755