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The Impact of Simultaneous Liver Resection for Occult Liver Metastases of Pancreatic Adenocarcinoma
Joint Authors
Pullankavumkal, J. R.
Gül, Safak
Guckelberger, Olaf
Bahra, Marcus
Pelzer, Uwe
Puhl, Gero
Klein, Fritz
Neuhaus, Peter
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Backround.
Pancreas resection is the only curative treatment for pancreatic adenocarcinoma.
In the event of unexpected incidental liver metastases during operative exploration patients were traditionally referred to palliative treatment arms.
With continuous progress in the surgical expertise simultaneous pancreas and liver resections seem technically feasible nowadays.
The aim of this study therefore was to analyze the impact of synchronous liver-directed therapy on operative outcome and overall survival in patients with hepatic metastasized pancreatic adenocarcinoma (HMPA).
Methods.
22 patients who underwent simultaneous pancreas resection and liver-directed therapy for HMPA between January 1, 2004 and January 1, 2009 were compared to 22 patients who underwent classic pancreas resection for nonmetastasized pancreatic adenocarcinoma (NMPA) in a matched pair study design.
Postoperative morbidity, preoperative, and operative data and overall survival were analyzed.
Results.
Overall survival was significantly decreased in the HMPA group.
Postoperative morbidity and mortality and median operation time did not significantly differ between the groups.
Conclusion.
The results of our study showed that simultaneous pancreas resection and liver-directed therapy may safely be performed and may therefore be applied in individual patients with HMPA.
However, a potential benefit of this radical surgical approach with regard to overall survival and/or quality of life remains to be proven.
American Psychological Association (APA)
Klein, Fritz& Puhl, Gero& Guckelberger, Olaf& Pelzer, Uwe& Pullankavumkal, J. R.& Gül, Safak…[et al.]. 2012. The Impact of Simultaneous Liver Resection for Occult Liver Metastases of Pancreatic Adenocarcinoma. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-509828
Modern Language Association (MLA)
Klein, Fritz…[et al.]. The Impact of Simultaneous Liver Resection for Occult Liver Metastases of Pancreatic Adenocarcinoma. Gastroenterology Research and Practice No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-509828
American Medical Association (AMA)
Klein, Fritz& Puhl, Gero& Guckelberger, Olaf& Pelzer, Uwe& Pullankavumkal, J. R.& Gül, Safak…[et al.]. The Impact of Simultaneous Liver Resection for Occult Liver Metastases of Pancreatic Adenocarcinoma. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-509828
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509828