Pleurodesis Induction in Rats by Copaiba (Copaifera multijuga Hayne) Oil
Joint Authors
Lima, Luis Carlos
Reichl, Alfredo Coimbra
Westphal, Fernando Luiz
Pêgo-Fernandes, Paulo Manuel
Veiga-Junior, Valdir F.
Canzian, Mauro
Pieri, Fabio Alessandro
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This study aims to assess and compare copaiba oleoresin of Copaifera multijuga and 0.5% silver nitrate for the induction of pleurodesis in an experimental model.
Ninety-six male Wistar rats were divided into three groups: control (0.9% saline solution), copaiba (copaiba oil), and silver nitrate (0.5% silver nitrate).
The substances were injected into the right pleural cavity and the alterations were observed macroscopically and microscopically at 24, 48, 72, and 504 h.
The value of macroscopic alterations grade and acute inflammatory reaction grade means was higher in the 24 h copaiba group in relation to silver nitrate.
Fibrosis and neovascularization means in the visceral pleura were higher in 504 h copaiba group in relation to the silver nitrate group.
The grade of the alveolar edema mean was higher in the silver nitrate group in relation to the copaiba group, in which this alteration was not observed.
The presence of bronchopneumonia was higher in the 24 h silver nitrate group (n = 4) in relation to the copaiba group (n = 0).
In conclusion, both groups promoted pleurodesis, with better results in copaiba group and the silver nitrate group presented greater aggression to the pulmonary parenchyma.
American Psychological Association (APA)
Westphal, Fernando Luiz& Canzian, Mauro& Pieri, Fabio Alessandro& Reichl, Alfredo Coimbra& Pêgo-Fernandes, Paulo Manuel& Lima, Luis Carlos…[et al.]. 2014. Pleurodesis Induction in Rats by Copaiba (Copaifera multijuga Hayne) Oil. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-509858
Modern Language Association (MLA)
Westphal, Fernando Luiz…[et al.]. Pleurodesis Induction in Rats by Copaiba (Copaifera multijuga Hayne) Oil. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-509858
American Medical Association (AMA)
Westphal, Fernando Luiz& Canzian, Mauro& Pieri, Fabio Alessandro& Reichl, Alfredo Coimbra& Pêgo-Fernandes, Paulo Manuel& Lima, Luis Carlos…[et al.]. Pleurodesis Induction in Rats by Copaiba (Copaifera multijuga Hayne) Oil. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-509858
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509858