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Biological Treatments : New Weapons in the Management of Monogenic Autoinflammatory Disorders
Joint Authors
Brizi, Maria Giuseppina
Muscari, Isabella
Vitale, Antonio
Cantarini, Luca
Guerrini, Susanna
Punzi, Leonardo
Patti, Maria
Rigante, Donato
Caso, Francesco
Lucherini, Orso Maria
Galeazzi, Mauro
Magnotti, Flora
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-21
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Treatment of monogenic autoinflammatory disorders, an expanding group of hereditary diseases characterized by apparently unprovoked recurrent episodes of inflammation, without high-titre autoantibodies or antigen-specific T cells, has been revolutionized by the discovery that several of these conditions are caused by mutations in proteins involved in the mechanisms of innate immune response, including components of the inflammasome, cytokine receptors, receptor antagonists, and oversecretion of a network of proinflammatory molecules.
Aim of this review is to synthesize the current experience and the most recent evidences about the therapeutic approach with biologic drugs in pediatric and adult patients with monogenic autoinflammatory disorders.
American Psychological Association (APA)
Vitale, Antonio& Rigante, Donato& Lucherini, Orso Maria& Caso, Francesco& Muscari, Isabella& Magnotti, Flora…[et al.]. 2013. Biological Treatments : New Weapons in the Management of Monogenic Autoinflammatory Disorders. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-509868
Modern Language Association (MLA)
Vitale, Antonio…[et al.]. Biological Treatments : New Weapons in the Management of Monogenic Autoinflammatory Disorders. Mediators of Inflammation No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-509868
American Medical Association (AMA)
Vitale, Antonio& Rigante, Donato& Lucherini, Orso Maria& Caso, Francesco& Muscari, Isabella& Magnotti, Flora…[et al.]. Biological Treatments : New Weapons in the Management of Monogenic Autoinflammatory Disorders. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-509868
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509868