Biological Treatments : New Weapons in the Management of Monogenic Autoinflammatory Disorders

Joint Authors

Brizi, Maria Giuseppina
Muscari, Isabella
Vitale, Antonio
Cantarini, Luca
Guerrini, Susanna
Punzi, Leonardo
Patti, Maria
Rigante, Donato
Caso, Francesco
Lucherini, Orso Maria
Galeazzi, Mauro
Magnotti, Flora

Source

Mediators of Inflammation

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-16, 16 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-07-21

Country of Publication

Egypt

No. of Pages

16

Main Subjects

Diseases

Abstract EN

Treatment of monogenic autoinflammatory disorders, an expanding group of hereditary diseases characterized by apparently unprovoked recurrent episodes of inflammation, without high-titre autoantibodies or antigen-specific T cells, has been revolutionized by the discovery that several of these conditions are caused by mutations in proteins involved in the mechanisms of innate immune response, including components of the inflammasome, cytokine receptors, receptor antagonists, and oversecretion of a network of proinflammatory molecules.

Aim of this review is to synthesize the current experience and the most recent evidences about the therapeutic approach with biologic drugs in pediatric and adult patients with monogenic autoinflammatory disorders.

American Psychological Association (APA)

Vitale, Antonio& Rigante, Donato& Lucherini, Orso Maria& Caso, Francesco& Muscari, Isabella& Magnotti, Flora…[et al.]. 2013. Biological Treatments : New Weapons in the Management of Monogenic Autoinflammatory Disorders. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-509868

Modern Language Association (MLA)

Vitale, Antonio…[et al.]. Biological Treatments : New Weapons in the Management of Monogenic Autoinflammatory Disorders. Mediators of Inflammation No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-509868

American Medical Association (AMA)

Vitale, Antonio& Rigante, Donato& Lucherini, Orso Maria& Caso, Francesco& Muscari, Isabella& Magnotti, Flora…[et al.]. Biological Treatments : New Weapons in the Management of Monogenic Autoinflammatory Disorders. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-509868

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-509868