The Role of Molecular Microtubule Motors and the Microtubule Cytoskeleton in Stress Granule Dynamics
Joint Authors
Bartoli, Kristen M.
Saunders, William S.
Bishop, Darryl L.
Source
International Journal of Cell Biology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Stress granules (SGs) are cytoplasmic foci that appear in cells exposed to stress-induced translational inhibition.
SGs function as a triage center, where mRNAs are sorted for storage, degradation, and translation reinitiation.
The underlying mechanisms of SGs dynamics are still being characterized, although many key players have been identified.
The main components of SGs are stalled 48S preinitiation complexes.
To date, many other proteins have also been found to localize in SGs and are hypothesized to function in SG dynamics.
Most recently, the microtubule cytoskeleton and associated motor proteins have been demonstrated to function in SG dynamics.
In this paper, we will discuss current literature examining the function of microtubules and the molecular microtubule motors in SG assembly, coalescence, movement, composition, organization, and disassembly.
American Psychological Association (APA)
Bartoli, Kristen M.& Bishop, Darryl L.& Saunders, William S.. 2011. The Role of Molecular Microtubule Motors and the Microtubule Cytoskeleton in Stress Granule Dynamics. International Journal of Cell Biology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-509869
Modern Language Association (MLA)
Bartoli, Kristen M.…[et al.]. The Role of Molecular Microtubule Motors and the Microtubule Cytoskeleton in Stress Granule Dynamics. International Journal of Cell Biology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-509869
American Medical Association (AMA)
Bartoli, Kristen M.& Bishop, Darryl L.& Saunders, William S.. The Role of Molecular Microtubule Motors and the Microtubule Cytoskeleton in Stress Granule Dynamics. International Journal of Cell Biology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-509869
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509869