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Oral Panax notoginseng Preparation for Coronary Heart Disease : A Systematic Review of Randomized Controlled Trials
Joint Authors
Liu, Jian-Ping
Xu, Hao
Shang, Qing-hua
Liu, Zhaolan
Chen, Ke-Ji
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-20
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
This systematic review aims to evaluate current evidence for the benefit and side effect of oral Panax notoginseng preparation for coronary heart disease (CHD).
We included 17 randomized clinical trials (17 papers and 1747 participants).
Comparing with no intervention on the basis of conventional therapy, oral Panax notoginseng did not show significant effect on reducing cardiovascular events, but it could alleviate angina pectoris (including improving the symptoms of angina pectoris [RR 1.20; 95% CI 1.12 to 1.28; 7 trials, n=791], improving electrocardiogram [RR 1.35; 95% CI 1.19 to 1.53; 8 trials, n=727], decreasing the recurrence of angina pectoris [RR 0.38; 95% CI 0.16 to 0.94; 1 trials, n=60], duration of angina pectoris [RR −1.88; 95% CI −2.08 to −1.69; 2 trials, n=292], and dosage of nitroglycerin [MD −1.13; 95% CI −1.70 to −0.56; 2 trials, n=212]); oral Panax notoginseng had no significant difference compared with isosorbide dinitrate on immediate effect for angina pectoris [RR 0.96; 95% CI 0.81 to 1.15; 1 trial, n=80].
In conclusion, oral Panax notoginseng preparation could relieve angina pectoris related symptoms.
However, the small sample size and potential bias of most trials influence the convincingness of this conclusion.
More rigorous trials with high quality are needed to give high level of evidence, especially for the potential benefit of cardiovascular events.
American Psychological Association (APA)
Shang, Qing-hua& Xu, Hao& Liu, Zhaolan& Chen, Ke-Ji& Liu, Jian-Ping. 2013. Oral Panax notoginseng Preparation for Coronary Heart Disease : A Systematic Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-509883
Modern Language Association (MLA)
Shang, Qing-hua…[et al.]. Oral Panax notoginseng Preparation for Coronary Heart Disease : A Systematic Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-509883
American Medical Association (AMA)
Shang, Qing-hua& Xu, Hao& Liu, Zhaolan& Chen, Ke-Ji& Liu, Jian-Ping. Oral Panax notoginseng Preparation for Coronary Heart Disease : A Systematic Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-509883
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509883