An Uncommon Cause of Gastrointestinal Bleeding in an 84-Year-Old Female

Abstract EN

The estimated annual incidence for drug-induced thrombocytopenia is 10 per million.

Although fatal consequences are uncommon, life-threatening hemorrhage can occur due to spontaneous bleeding.

We report a case of 84-year-old Caucasian female who presented to the emergency department with multiple episodes of bloody bowel movements.

One week prior to this admission, she was started on trimethoprim-sulfamethoxazole for the treatment of skin abscess.

On admission laboratory results showed platelet count of 4 × 103/mm3 and hemoglobin of 10.2 g/dL.

Because of unstable vital signs, the patient was transferred to the intensive care unit where she received multiple units of platelet and blood transfusion.

Drug-induced thrombocytopenia due to TMP/SMX was suspected.

Intravenous methylprednisolone was started as well as immune globulin with good clinical response.