Pomegranate Supplementation Improves Affective and Motor Behavior in Mice after Radiation Exposure
Joint Authors
Hartman, Richard E.
Dulcich, Melissa S.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Currently, NASA has plans for extended space travel, and previous research indicates that space radiation can have negative effects on cognitive skills as well as physical and mental health.
With long-term space travel, astronauts will be exposed to greater radiation levels.
Research shows that an antioxidant-enriched diet may offer some protection against the cellular effects of radiation and may provide significant neuroprotection from the effects of radiation-induced cognitive and behavioral skill deficits.
Ninety-six C57BL/6 mice (48 pomegranate fed and 48 control) were irradiated with proton radiation (2 Gy), and two-month postradiation behaviors were assessed using a battery of behavioral tests to measure cognitive and motor functions.
Proton irradiation was associated with depression-like behaviors in the tail suspension test, but this effect was ameliorated by the pomegranate diet.
Males, in general, displayed worse coordination and balance than females on the rotarod task, and the pomegranate diet ameliorated this effect.
Overall, it appears that proton irradiation, which may be encountered in space, may induce a different pattern of behavioral deficits in males than females and that a pomegranate diet may confer protection against some of those effects.
American Psychological Association (APA)
Dulcich, Melissa S.& Hartman, Richard E.. 2013. Pomegranate Supplementation Improves Affective and Motor Behavior in Mice after Radiation Exposure. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-509953
Modern Language Association (MLA)
Dulcich, Melissa S.& Hartman, Richard E.. Pomegranate Supplementation Improves Affective and Motor Behavior in Mice after Radiation Exposure. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-509953
American Medical Association (AMA)
Dulcich, Melissa S.& Hartman, Richard E.. Pomegranate Supplementation Improves Affective and Motor Behavior in Mice after Radiation Exposure. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-509953
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-509953