Differential Pulse Voltammetric Determination of Fulvestrant in Pharmaceutical Dosage Forms and Serum Samples

Joint Authors

Dogan-Topal, Burcu
Kul, Dilek
Ozkan, Sibel A.
Uslu, Bengi

Source

International Journal of Electrochemistry

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-02-14

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Chemistry

Abstract EN

The electrooxidation behavior and determination of fulvestrant at a glassy carbon electrode were investigated.

The voltammetric study of the model compounds allowed elucidating the possible oxidation mechanism of fulvestrant.

The dependence of the peak current and peak potentials on pH, concentration, nature of the buffer, and scan rate was determined.

The oxidation of fulvestrant showed a single and irreversible peak at glassy carbon electrode, and the process was found diffusion controlled.

Linear responses were obtained for the concentrations between 4×10−6 M and 6×10−5 M in standard samples and between 2×10−5 M and 1×10−4 M in serum samples.

The repeatability of the method was found 0.93 RSD%.

The repeatability, reproducibility, precision, and accuracy of proposed method were investigated.

American Psychological Association (APA)

Kul, Dilek& Dogan-Topal, Burcu& Ozkan, Sibel A.& Uslu, Bengi. 2011. Differential Pulse Voltammetric Determination of Fulvestrant in Pharmaceutical Dosage Forms and Serum Samples. International Journal of Electrochemistry،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-510026

Modern Language Association (MLA)

Kul, Dilek…[et al.]. Differential Pulse Voltammetric Determination of Fulvestrant in Pharmaceutical Dosage Forms and Serum Samples. International Journal of Electrochemistry No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-510026

American Medical Association (AMA)

Kul, Dilek& Dogan-Topal, Burcu& Ozkan, Sibel A.& Uslu, Bengi. Differential Pulse Voltammetric Determination of Fulvestrant in Pharmaceutical Dosage Forms and Serum Samples. International Journal of Electrochemistry. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-510026

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-510026