Differential Pulse Voltammetric Determination of Fulvestrant in Pharmaceutical Dosage Forms and Serum Samples
Joint Authors
Dogan-Topal, Burcu
Kul, Dilek
Ozkan, Sibel A.
Uslu, Bengi
Source
International Journal of Electrochemistry
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The electrooxidation behavior and determination of fulvestrant at a glassy carbon electrode were investigated.
The voltammetric study of the model compounds allowed elucidating the possible oxidation mechanism of fulvestrant.
The dependence of the peak current and peak potentials on pH, concentration, nature of the buffer, and scan rate was determined.
The oxidation of fulvestrant showed a single and irreversible peak at glassy carbon electrode, and the process was found diffusion controlled.
Linear responses were obtained for the concentrations between 4×10−6 M and 6×10−5 M in standard samples and between 2×10−5 M and 1×10−4 M in serum samples.
The repeatability of the method was found 0.93 RSD%.
The repeatability, reproducibility, precision, and accuracy of proposed method were investigated.
American Psychological Association (APA)
Kul, Dilek& Dogan-Topal, Burcu& Ozkan, Sibel A.& Uslu, Bengi. 2011. Differential Pulse Voltammetric Determination of Fulvestrant in Pharmaceutical Dosage Forms and Serum Samples. International Journal of Electrochemistry،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-510026
Modern Language Association (MLA)
Kul, Dilek…[et al.]. Differential Pulse Voltammetric Determination of Fulvestrant in Pharmaceutical Dosage Forms and Serum Samples. International Journal of Electrochemistry No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-510026
American Medical Association (AMA)
Kul, Dilek& Dogan-Topal, Burcu& Ozkan, Sibel A.& Uslu, Bengi. Differential Pulse Voltammetric Determination of Fulvestrant in Pharmaceutical Dosage Forms and Serum Samples. International Journal of Electrochemistry. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-510026
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510026