![](/images/graphics-bg.png)
Analysis of Pericardial Effusion from Idiopathic Pericarditis Patients by Two-Dimensional Gel Electrophoresis
Joint Authors
Yavuz, Sadan
Akpinar, Gurler
Ozbudak, Ersan
Berki, Turan
Kasap, Murat
Ural, Dilek
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Pericardial fluid (PF) is often considered to be reflection of the serum by which information regarding the physiological status of the heart can be obtained.
Some local and systemic disorders may perturb the balance between synthesis and discharge of PF and may cause its aberrant accumulation in the pericardial cavity as pericardial effusion (PE).
PE may then lead to an increased intrapericardial pressure from which the heart function is undesirably affected.
For some cases, the causes for the perturbance of fluid balance are well understood, but in some other cases, they are not apparent.
It may, thus, be helpful to understand the molecular mechanisms behind this troublesome condition to elucidate a clinical approach for therapeutic uses.
In this study, protein profiles of PEs from idiopathic pericarditis patients were analyzed.
Control samples from patients undergoing elective cardiac surgery (ECS) were included for comparison.
In addition to high abundant serum-originated proteins that may not hold significance for understanding the molecular mechanisms behind this disease, omentin-1 was identified and its level was higher for more than two-fold in PE of IP patients.
Increased levels of omentin-1 in PE may open a way for understanding the molecular mechanisms behind idiopathic pericarditis (IP).
American Psychological Association (APA)
Yavuz, Sadan& Kasap, Murat& Akpinar, Gurler& Ozbudak, Ersan& Ural, Dilek& Berki, Turan. 2014. Analysis of Pericardial Effusion from Idiopathic Pericarditis Patients by Two-Dimensional Gel Electrophoresis. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-510141
Modern Language Association (MLA)
Yavuz, Sadan…[et al.]. Analysis of Pericardial Effusion from Idiopathic Pericarditis Patients by Two-Dimensional Gel Electrophoresis. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-510141
American Medical Association (AMA)
Yavuz, Sadan& Kasap, Murat& Akpinar, Gurler& Ozbudak, Ersan& Ural, Dilek& Berki, Turan. Analysis of Pericardial Effusion from Idiopathic Pericarditis Patients by Two-Dimensional Gel Electrophoresis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-510141
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510141