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Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem Cell Exhaustion Syndromes?
Joint Authors
Zambón, Daniel
Larsen, Gustavo
Núñez, Luis
Riordan, Neil H.
Marin, Gustavo Horacio
Soratti, Carlos
Spretz, Rubén
van Leeuwen, Michiel
Drago, Hugo
Ichim, Thomas
Sturla, Flavio
Tau, José María
Mansilla, Eduardo
Mártire, Karina
Díaz Aquino, Vanina
Patel, Amit
Roque, Gustavo
Maceira, Alberto
Ibar, Ricardo
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-13
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
One of the most important and complex diseases of modern society is metabolic syndrome.
This syndrome has not been completely understood, and therefore an effective treatment is not available yet.
We propose a possible stem cell mechanism involved in the development of metabolic syndrome.
This way of thinking lets us consider also other significant pathologies that could have similar etiopathogenic pathways, like lipodystrophic syndromes, progeria, and aging.
All these clinical situations could be the consequence of a progressive and persistent stem cell exhaustion syndrome (SCES).
The main outcome of this SCES would be an irreversible loss of the effective regenerative mesenchymal stem cells (MSCs) pools.
In this way, the normal repairing capacities of the organism could become inefficient.
Our point of view could open the possibility for a new strategy of treatment in metabolic syndrome, lipodystrophic syndromes, progeria, and even aging: stem cell therapies.
American Psychological Association (APA)
Mansilla, Eduardo& Díaz Aquino, Vanina& Zambón, Daniel& Marin, Gustavo Horacio& Mártire, Karina& Roque, Gustavo…[et al.]. 2011. Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem Cell Exhaustion Syndromes?. Stem Cells International،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-510189
Modern Language Association (MLA)
Mansilla, Eduardo…[et al.]. Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem Cell Exhaustion Syndromes?. Stem Cells International No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-510189
American Medical Association (AMA)
Mansilla, Eduardo& Díaz Aquino, Vanina& Zambón, Daniel& Marin, Gustavo Horacio& Mártire, Karina& Roque, Gustavo…[et al.]. Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem Cell Exhaustion Syndromes?. Stem Cells International. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-510189
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510189