Managing Inflammation after Spinal Cord Injury through Manipulation of Macrophage Function
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Spinal cord injury (SCI) triggers inflammation with activation of innate immune responses that contribute to secondary injury including oligodendrocyte apoptosis, demyelination, axonal degeneration, and neuronal death.
Macrophage activation, accumulation, and persistent inflammation occur in SCI.
Macrophages are heterogeneous cells with extensive functional plasticity and have the capacity to switch phenotypes by factors present in the inflammatory microenvironment of the injured spinal cord.
This review will discuss the role of different polarized macrophages and the potential effect of macrophage-based therapies for SCI.
American Psychological Association (APA)
Ren, Yi& Young, Wise. 2013. Managing Inflammation after Spinal Cord Injury through Manipulation of Macrophage Function. Neural Plasticity،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-510248
Modern Language Association (MLA)
Ren, Yi& Young, Wise. Managing Inflammation after Spinal Cord Injury through Manipulation of Macrophage Function. Neural Plasticity No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-510248
American Medical Association (AMA)
Ren, Yi& Young, Wise. Managing Inflammation after Spinal Cord Injury through Manipulation of Macrophage Function. Neural Plasticity. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-510248
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510248