Characteristics and Results of the Management of Diffuse Large B-Cell Lymphomas : The Experience of Côte d'Ivoire
Joint Authors
Nanho, Danho Clotaire
Aïssata, Tolo Diebkilé
Sékongo, Yassongui Mamadou
Koffi, Gustave K.
Meité, N'Dogomo
Roméo, Ayémou
Kouakou, Boidy
Sanogo, Ibrahima
Emeuraude, N'Dhatz
Kouéhion, Paul
Mozart, Konan
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Diffuse large B-cell lymphomas have been little studied in black Africans.
The purpose of our study was to determine the characteristics and results of the management of these lymphomas.
Patients and Methods.
In a descriptive and analytic retrospective study we studied the medical records of 63 patients with diffuse large B-cell lymphoma hospitalized during the period from 1991 to 2007.
The diagnosis was made after lymph node or organ biopsy.
Response to treatment, OS, PFS, and toxicity were studied.
The complete response has been analyzed univariate and multivariate analysis.
Results.
The median age was 42 years.
The sex ratio was 2.
The HIV serology was positive in 11 cases, and 8 patients had antiretroviral therapy.
In 71% the lymphoma was at stages III and IV of Ann Arbor.
IPI was ≥3 in 65%.
Complete remission was achieved in 43%.
Only 43% of patients had had a good compliance.
Progression-free survival at 3 years was 32%, and overall survival at 3 years was 50%.
13% of patients were lost to follow up, and 51% of them died.
In terms of analysis the complete remission rate was influenced by the stage of Ann Arbor (P<0.0001), biological b symptoms (P<0.01), the IPI (P<0.0001), and the socioeconomic standing (P=0.001).
In multivariate analysis, only IPI and stage of Ann Arbor influence the complete remission.
American Psychological Association (APA)
Aïssata, Tolo Diebkilé& Kouakou, Boidy& Emeuraude, N'Dhatz& Nanho, Danho Clotaire& Meité, N'Dogomo& Roméo, Ayémou…[et al.]. 2012. Characteristics and Results of the Management of Diffuse Large B-Cell Lymphomas : The Experience of Côte d'Ivoire. Advances in Hematology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-510262
Modern Language Association (MLA)
Aïssata, Tolo Diebkilé…[et al.]. Characteristics and Results of the Management of Diffuse Large B-Cell Lymphomas : The Experience of Côte d'Ivoire. Advances in Hematology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-510262
American Medical Association (AMA)
Aïssata, Tolo Diebkilé& Kouakou, Boidy& Emeuraude, N'Dhatz& Nanho, Danho Clotaire& Meité, N'Dogomo& Roméo, Ayémou…[et al.]. Characteristics and Results of the Management of Diffuse Large B-Cell Lymphomas : The Experience of Côte d'Ivoire. Advances in Hematology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-510262
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510262