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A Schistosomiasis Model with Praziquantel Resistance
Joint Authors
Source
Discrete Dynamics in Nature and Society
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-06
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
A compartmental model is established for schistosomiasis with praziquantel resistance.
The model considers the impact of genetic resistance and drug treatment on the transmission of schistosomiasis.
We calculate the basic reproductive number and discuss the existence and stability of disease-free equilibrium, boundary equilibrium, and coexistence equilibrium.
Our analysis shows that regardless of whether drug treatment leads to the emergence of resistance, once the impact of genetic resistance is larger, the resistant strain will be dominant, which is detrimental to the control of schistosomiasis.
In addition, once the proportion of human with drug-resistant strain produced by drug treatment is larger, the number of human and snails with resistant strain is larger.
This is not a good result for drug treatment with praziquantel.
American Psychological Association (APA)
Qi, Longxing& Cui, Jing'an. 2013. A Schistosomiasis Model with Praziquantel Resistance. Discrete Dynamics in Nature and Society،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-510316
Modern Language Association (MLA)
Qi, Longxing& Cui, Jing'an. A Schistosomiasis Model with Praziquantel Resistance. Discrete Dynamics in Nature and Society No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-510316
American Medical Association (AMA)
Qi, Longxing& Cui, Jing'an. A Schistosomiasis Model with Praziquantel Resistance. Discrete Dynamics in Nature and Society. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-510316
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510316