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Risk Factors for Infection with Different Hepatitis C Virus Genotypes in Southern Brazil
Joint Authors
Sbeghen, Marina Dallagasperina
Paraboni, Marisa Lúcia Romani
Wolff, Fernando Herz
Moreira, Leila Beltrami
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Objectives.
To investigate the proportion of different genotypes in countryside microregions in southern Brazil, and their association with risk factors.
Methods.
Cross-sectional study including a convenience sample of patients who tested positive for HCV-RNA and were referred to a regional health center for genotyping, from December 2003 to January 2008.
Data were obtained through the National Disease Surveillance Data System, from laboratory registers and from patient charts.
Identification of genotypes was carried out using the Restriction Fragment Length Polymorphism “in house” technique.
Independent associations with genotypes were evaluated in multinomial logistic regression and prevalence rates of genotypes were estimated with modified Poisson regression.
Results.
The sample consisted of 441 individuals, 41.1±12.0 years old, 56.5% men.
Genotype 1 was observed in 41.5% (95% CI 37.9–48.1) of patients, genotype 2 in 19.3% (95% CI 15.0–23.6), and genotype 3 in 39.2% (95% CI 35.6–43.0).
HCV genotype was significantly associated with gender and age.
Dental procedures were associated with higher proportion of genotype 2 independently of age, education, and patient treatment center.
Conclusions.
The hepatitis C virus genotype 1 was the most frequent.
Genotype 2 was associated with female gender, age, and dental procedure exposition.
American Psychological Association (APA)
Paraboni, Marisa Lúcia Romani& Sbeghen, Marina Dallagasperina& Wolff, Fernando Herz& Moreira, Leila Beltrami. 2012. Risk Factors for Infection with Different Hepatitis C Virus Genotypes in Southern Brazil. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-510429
Modern Language Association (MLA)
Paraboni, Marisa Lúcia Romani…[et al.]. Risk Factors for Infection with Different Hepatitis C Virus Genotypes in Southern Brazil. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-510429
American Medical Association (AMA)
Paraboni, Marisa Lúcia Romani& Sbeghen, Marina Dallagasperina& Wolff, Fernando Herz& Moreira, Leila Beltrami. Risk Factors for Infection with Different Hepatitis C Virus Genotypes in Southern Brazil. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-510429
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510429