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Multilayer Mie Scattering Model for Investigation of Intracellular Structural Changes in the Nucleolus and Cytoplasm
Joint Authors
Steinberg, I.
Saltsberger, S.
Gannot, Israel
Source
International Journal of Optics
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Light scattering from biological cells has been used for many years as a diagnostic tool.
Several simulation methods of the scattering process were developed in the last decades in order to understand and predict the scattering patterns.
We developed an analytical model of a multilayer spherical scattering cell.
Here, we describe the model and show that the results obtained within this simple method are similar to those obtained with far more complicated methods such as finite-difference time-domain (FDTD).
The multilayer model is then used to study the effects of changes in the distribution of internal cell structures like mitochondria distribution or nucleus internal structures that exist in biological cells.
Such changes are related with cancerous processes within the cell as well as other cell pathologies.
Results show the ability to discriminate between different cell stages related to the mitochondria distributions and to internal structure of the nucleolus.
American Psychological Association (APA)
Saltsberger, S.& Steinberg, I.& Gannot, Israel. 2011. Multilayer Mie Scattering Model for Investigation of Intracellular Structural Changes in the Nucleolus and Cytoplasm. International Journal of Optics،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-510494
Modern Language Association (MLA)
Saltsberger, S.…[et al.]. Multilayer Mie Scattering Model for Investigation of Intracellular Structural Changes in the Nucleolus and Cytoplasm. International Journal of Optics No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-510494
American Medical Association (AMA)
Saltsberger, S.& Steinberg, I.& Gannot, Israel. Multilayer Mie Scattering Model for Investigation of Intracellular Structural Changes in the Nucleolus and Cytoplasm. International Journal of Optics. 2011. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-510494
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510494