Feasibility of Endoscopic Submucosal Dissection : A New Technique for En Bloc Resection of a Large Superficial Tumor in the Colon and Rectum

Abstract EN

Endoscopic submucosal dissection (ESD) is a promising procedure that enables en bloc resection of large superficial tumors in the upper gastrointestinal tract.

On the other hand, ESD in the colon and rectum is technically difficult to perform because of its anatomical features.

At our institution, 137 consecutive superficial colorectal tumors larger than 20 mm in diameter in 137 patients were treated by ESD between April 2007 and October 2010, and 132 lesions were successfully resected.

The average procedure time was 79.2 minutes, and the rate of en bloc resection was 89.1% (122/137).

The rate of complete resection, defined as en bloc resection with tumor-free lateral and vertical margins, was 85.4% (117/137).

The rate of perforation was 3.6% (5/137).

Colorectal ESD achieved a high rate of en bloc resection and complete resection and is applicable in the colorectum.