Regulatory T Cells and the Control of the Allergic Response
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The study of immune regulation and tolerance has been traditionally associated with self/nonself-discrimination.
However, the finding that dominant tolerance, a model that puts in evidence the active role of regulatory T cells, can develop to nonself-antigens suggests that the imposition of tolerance can be context dependent.
This paper reviews the emerging field of acquired immune tolerance to non-self antigens, with an emphasis on the different subsets of induced regulatory T cells that appear to specialize in specific functional niches.
Such regulatory mechanisms are important in preventing the onset of allergic diseases in healthy individuals.
In addition, it may be possible to take advantage of these immune regulatory mechanisms for the induction of tolerance in cases where pathological immune responses are generated to allergens occurring in nature, but also to other immunogens such as biological drugs developed for medical therapies.
American Psychological Association (APA)
Agua-Doce, Ana& Graca, Luis. 2012. Regulatory T Cells and the Control of the Allergic Response. Journal of Allergy،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-510614
Modern Language Association (MLA)
Agua-Doce, Ana& Graca, Luis. Regulatory T Cells and the Control of the Allergic Response. Journal of Allergy No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-510614
American Medical Association (AMA)
Agua-Doce, Ana& Graca, Luis. Regulatory T Cells and the Control of the Allergic Response. Journal of Allergy. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-510614
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510614