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Association between Hypoadiponectinemia and Low Serum Concentrations of Calcium and Vitamin D in Women with Polycystic Ovary Syndrome
Joint Authors
Mazloomi, Sahar
Kalantari, Sadroddin
Sharifi, Faranak
Eshaq Hosseini, Seyed Mahmood
Mazloomzadeh, Saideh
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To investigate the possible association of calcium and vitamin D deficiency with hypoadiponectinemia in women with PCOS.
Subjects and Methods.
In this case-control study, 103 PCOS cases and 103 controls included.
The concentrations of calcium, 25-OH-vitamin D (25OHD), adiponectin, insulin, glucose, total cholesterol, HDL-cholesterol, triglyceride (TG), and androgens were measured in fasting blood samples.
Results.
Adiponectin (8.4±2.7 ng/mL versus 13.6±5 ng/mL in control group, P:0.00), calcium (2±0.1 mmol/L versus 2.55±0.17 mmol/L in controls, P:0.00), and 25-OH-Vit D (30±2.99 nmol/L versus 43.7±5.2 nmol/L in control group, P:0.00) levels were decreased in women with PCOS.
Subjects with PCOS had higher concentrations of TG (1.4±0.77 mmol/L versus 1.18±0.75 mmol/L in control group, P: 0.019) and dehydroepiandrosterone sulfate (DHEA-S) (10.7±11 mmol/L versus 9.7±10.4, P:0.02 in control group).
There were significant correlations between adiponectin concentrations with calcium (r:0.78, P:0.00) and 25OHD levels (r:0.82, P:0.00).
The association of hypoadiponectinemia and PCOS was not significant considering 25OHD as a confounding factor.
Conclusion.
The present findings indicate that the association of hypoadiponectinemia with PCOS is dependent on vitamin D.
A possible beneficiary effect of vitamin D on the metabolic parameters in PCOS may be suggested.
American Psychological Association (APA)
Mazloomi, Sahar& Sharifi, Faranak& Eshaq Hosseini, Seyed Mahmood& Kalantari, Sadroddin& Mazloomzadeh, Saideh. 2012. Association between Hypoadiponectinemia and Low Serum Concentrations of Calcium and Vitamin D in Women with Polycystic Ovary Syndrome. ISRN Endocrinology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-510659
Modern Language Association (MLA)
Mazloomi, Sahar…[et al.]. Association between Hypoadiponectinemia and Low Serum Concentrations of Calcium and Vitamin D in Women with Polycystic Ovary Syndrome. ISRN Endocrinology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-510659
American Medical Association (AMA)
Mazloomi, Sahar& Sharifi, Faranak& Eshaq Hosseini, Seyed Mahmood& Kalantari, Sadroddin& Mazloomzadeh, Saideh. Association between Hypoadiponectinemia and Low Serum Concentrations of Calcium and Vitamin D in Women with Polycystic Ovary Syndrome. ISRN Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-510659
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510659