Haemophilus influenzae Type b Meningitis in the Short Period after Vaccination : A Reminder of the Phenomenon of Apparent Vaccine Failure

Abstract EN

We present two cases of bacterial meningitis caused by Haemophilus influenzae type b (Hib) which developed a few days after conjugate Hib vaccination.

This phenomenon of postimmunization provocative time period is reviewed and discussed.

These cases serve as a reminder to clinicians of the risk, albeit rare, of invasive Hib disease in the short period after successful immunization.