Carotid Atherosclerosis, Endothelial Disfunction, and Arterial Stiffness in Young and Middle-Aged Men with Coronary Artery Disease
Joint Authors
Rogoza, Anatoly
Kuharchuk, Valery
Machmudova, Heda
Balachonova, Tatyana
Tripoten, Marya
Andreevskaya, Marina
Kozlov, Sergey
Source
International Journal of Vascular Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
To assess structural and functional status of the arteries in young and middle-aged men with recently developed CAD.
Methods and Results.
A total of 78 men aged 28 to 50 years underwent carotid ultrasound, endothelial function, and arterial stiffness measurements.
Angiographically proven CAD was present in 49 patients.
Carotid plaques were present in 45 (91.8%) patients with CAD and in 8 (27.6%) men without CAD (P<0.001).
Patients with CAD more often had multiple plaques (86.7% versus 13.8%, P<0.001).
The prevalence of carotid intima-media thickness (IMT) ≥0.9 mm and of abnormal brachial artery flow-mediated dilatation (FMD) was not differing in both groups.
The mean aortic pulse wave velocity (PWV) was 6.8±1.3 m/s for patients with CAD and 5.8±0.9 m/s for subjects without CAD (P<0.001).
Aortic PWV above the 75th percentile of the “normal” samples was found in 26 (53.1%) patients with CAD and in 7 (24.1%) subjects without CAD (P=0.02).
Aortic PWV was related to the severity of CAD.
Conclusions.
Carotid plaques and increased aortic PWV may be more powerful predictors of the occurrence of CAD in young and middle-aged men, than the presence of increased carotid IMT and abnormal brachial artery FMD.
American Psychological Association (APA)
Kozlov, Sergey& Balachonova, Tatyana& Machmudova, Heda& Tripoten, Marya& Andreevskaya, Marina& Rogoza, Anatoly…[et al.]. 2012. Carotid Atherosclerosis, Endothelial Disfunction, and Arterial Stiffness in Young and Middle-Aged Men with Coronary Artery Disease. International Journal of Vascular Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-510699
Modern Language Association (MLA)
Kozlov, Sergey…[et al.]. Carotid Atherosclerosis, Endothelial Disfunction, and Arterial Stiffness in Young and Middle-Aged Men with Coronary Artery Disease. International Journal of Vascular Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-510699
American Medical Association (AMA)
Kozlov, Sergey& Balachonova, Tatyana& Machmudova, Heda& Tripoten, Marya& Andreevskaya, Marina& Rogoza, Anatoly…[et al.]. Carotid Atherosclerosis, Endothelial Disfunction, and Arterial Stiffness in Young and Middle-Aged Men with Coronary Artery Disease. International Journal of Vascular Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-510699
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510699