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Motor Dysfunction Correlates with Frontal White Matter Ischemic Changes in Patients with Leukoaraiosis
Joint Authors
Ribeiro, Olga
Viana-Baptista, Miguel
Esperança-Pina, José António
Jordão, Constança
Ferro, José
Bugalho, Paulo
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Objectives.
To test the relation between white matter lesions (WML) location and physical performance, in aged patients.
Methods.
Subjects: 29 patients (17 males), aged >65 (mean age 72.6±5.2), with leukoaraiosis.
WML was quantified with a visual scale; Apparent Diffusion Coefficient (ADC) was measured bilaterally in frontal periventricular lesioned white matter and frontal and parieto-occipital normal appearing white matter (NAWM).
Motor performance was studied using the Short Physical Performance Battery (SPPB), single leg stand time, finger tapping and grooved pegboard tests (GPT).
Results.
There were significant correlations between the frontal region visual scale scores and SPPB chair stands (r=-0.379; P=.039) and Grooved Pegboard (r=0.393; P=.032); frontal NAWM ADC values and SPPB standing balance (r=-0.450; P=.014) and SPPB 4 meter walk (r=-0.379; P=.043).
Conclusion.
Frontal WML are negatively related to motor performance in patients with leukoaraiosis.
DWI results suggest that this may be true even for NAWM.
American Psychological Association (APA)
Viana-Baptista, Miguel& Bugalho, Paulo& Jordão, Constança& Ribeiro, Olga& Esperança-Pina, José António& Ferro, José. 2011. Motor Dysfunction Correlates with Frontal White Matter Ischemic Changes in Patients with Leukoaraiosis. Journal of Aging Research،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-510724
Modern Language Association (MLA)
Viana-Baptista, Miguel…[et al.]. Motor Dysfunction Correlates with Frontal White Matter Ischemic Changes in Patients with Leukoaraiosis. Journal of Aging Research No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-510724
American Medical Association (AMA)
Viana-Baptista, Miguel& Bugalho, Paulo& Jordão, Constança& Ribeiro, Olga& Esperança-Pina, José António& Ferro, José. Motor Dysfunction Correlates with Frontal White Matter Ischemic Changes in Patients with Leukoaraiosis. Journal of Aging Research. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-510724
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510724