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A Mechanism-Based Approach to Prevention of and Therapy for Fibromyalgia
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-02
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Fibromyalgia syndrome (FMS) is characterized by pain referred to deep tissues.
Diagnosis and treatment of FMS are complicated by a variable coexistence with regional pain, fatigue, sleep disruption, difficulty with mentation, and depression.
The widespread, deep pain of FMS can be a consequence of chronic psychological stress with autonomic dysregulation.
Stress acts centrally to facilitate pain and acts peripherally, via sympathetic vasoconstriction, to establish painful muscular ischemia.
FMS pain, with or without a coexistent regional pain condition, is stressful, setting up a vicious circle of reciprocal interaction.
Also, stress interacts reciprocally with systems of control over depression, mentation, and sleep, establishing FMS as a multiple-system disorder.
Thus, stress and the ischemic pain it generates are fundamental to the multiple disorders of FMS, and a therapeutic procedure that attenuates stress and peripheral vasoconstriction should be highly beneficial for FMS.
Physical exercise has been shown to counteract peripheral vasoconstriction and to attenuate stress, depression, and fatigue and improve mentation and sleep quality.
Thus, exercise can interrupt the reciprocal interactions between psychological stress and each of the multiple-system disorders of FMS.
The large literature supporting these conclusions indicates that exercise should be considered strongly as a first-line approach to FMS therapy.
American Psychological Association (APA)
Vierck, Charles J.. 2011. A Mechanism-Based Approach to Prevention of and Therapy for Fibromyalgia. Pain Research and Treatment،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-510838
Modern Language Association (MLA)
Vierck, Charles J.. A Mechanism-Based Approach to Prevention of and Therapy for Fibromyalgia. Pain Research and Treatment No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-510838
American Medical Association (AMA)
Vierck, Charles J.. A Mechanism-Based Approach to Prevention of and Therapy for Fibromyalgia. Pain Research and Treatment. 2011. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-510838
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510838