![](/images/graphics-bg.png)
Acute Phase Reactants as Novel Predictors of Cardiovascular Disease
Joint Authors
Meng, Qing H.
Jadhav, Ashok
Hassan, A.
Ahmed, M. S.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-06
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Acute phase reaction is a systemic response which usually follows a physiological condition that takes place in the beginning of an inflammatory process.
This physiological change usually lasts 1-2 days.
However, the systemic acute phase response usually lasts longer.
The aim of this systemic response is to restore homeostasis.
These events are accompanied by upregulation of some proteins (positive acute phase reactants) and downregulation of others (negative acute phase reactants) during inflammatory reactions.
Cardiovascular diseases are accompanied by the elevation of several positive acute phase reactants such as C-reactive protein (CRP), serum amyloid A (SAA), fibrinogen, white blood cell count, secretory nonpancreatic phospholipase 2-II (sPLA2-II), ferritin, and ceruloplasmin.
Cardiovascular disease is also accompanied by the reduction of negative acute phase reactants such as albumin, transferrin, transthyretin, retinol-binding protein, antithrombin, and transcortin.
In this paper, we will be discussing the biological activity and diagnostic and prognostic values of acute phase reactants with cardiovascular importance.
The potential therapeutic targets of these reactants will be also discussed.
American Psychological Association (APA)
Ahmed, M. S.& Jadhav, Ashok& Hassan, A.& Meng, Qing H.. 2012. Acute Phase Reactants as Novel Predictors of Cardiovascular Disease. ISRN Inflammation،Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-511052
Modern Language Association (MLA)
Ahmed, M. S.…[et al.]. Acute Phase Reactants as Novel Predictors of Cardiovascular Disease. ISRN Inflammation No. 2012 (2012), pp.1-18.
https://search.emarefa.net/detail/BIM-511052
American Medical Association (AMA)
Ahmed, M. S.& Jadhav, Ashok& Hassan, A.& Meng, Qing H.. Acute Phase Reactants as Novel Predictors of Cardiovascular Disease. ISRN Inflammation. 2012. Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-511052
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511052