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Photoinduced Synthesis of New Diisochromenochromen-4-ones and Their Antimicrobial Activities
Joint Authors
Jain, Payal
Yusuf, Mohamad
Solanki, Indu
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
The diisochromenochromen-4-one 3a-3b, 4a-4c, 5a-6a & 7 have been prepared from the photocyclization reaction of bischromen-4-one 2a-2e.
The later compounds are obtained from the O-alkylation of the suitable 3-hydroxy-2-aryl-4H-chromen-4-one 1a-1e with 4,4′-bischloromethyl-diphenyl in dry acetone, anhydrous K2CO3, and PTC (Bu4N+I−) under refluxing conditions.
The structures of compounds 2a-2e, 3a-3b, 4a-4c, 5a-6a & 7 have been characterized from the rigorous analysis of their IR, 1H-NMR, 13C-NMR, ESI-Mass, and elemental analysis.
The antibacterial and antifungal activities of the synthesized products were also evaluated against the Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Aspergillus janus and Penicillium glabrum, respectively.
Some of the tested compounds showed significant activity against the above-said microorganisms.
American Psychological Association (APA)
Yusuf, Mohamad& Solanki, Indu& Jain, Payal. 2012. Photoinduced Synthesis of New Diisochromenochromen-4-ones and Their Antimicrobial Activities. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-511194
Modern Language Association (MLA)
Yusuf, Mohamad…[et al.]. Photoinduced Synthesis of New Diisochromenochromen-4-ones and Their Antimicrobial Activities. The Scientific World Journal No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-511194
American Medical Association (AMA)
Yusuf, Mohamad& Solanki, Indu& Jain, Payal. Photoinduced Synthesis of New Diisochromenochromen-4-ones and Their Antimicrobial Activities. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-511194
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511194