Cellular Players in Skeletal Muscle Regeneration
Joint Authors
Popescu, Bogdan Ovidiu
Hinescu, Mihail Eugen
Ceafalan, Laura Cristina
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-23
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Abstract EN
Skeletal muscle, a tissue endowed with remarkable endogenous regeneration potential, is still under focused experimental investigation mainly due to treatment potential for muscle trauma and muscular dystrophies.
Resident satellite cells with stem cell features were enthusiastically described quite a long time ago, but activation of these cells is not yet controlled by any medical interventions.
However, after thorough reports of their existence, survival, activation, and differentiation there are still many questions to be answered regarding the intimate mechanism of tissue regeneration.
This review delivers an up-to-date inventory of the main known key players in skeletal muscle repair, revealed by various models of tissue injuries in mechanical trauma, toxic lesions, and muscular dystrophy.
A better understanding of the spatial and temporal relationships between various cell populations, with different physical or paracrine interactions and phenotype changes induced by local or systemic signalling, might lead to a more efficient approach for future therapies.
American Psychological Association (APA)
Ceafalan, Laura Cristina& Popescu, Bogdan Ovidiu& Hinescu, Mihail Eugen. 2014. Cellular Players in Skeletal Muscle Regeneration. BioMed Research International،Vol. 2014, no. 2014, pp.1-21.
https://search.emarefa.net/detail/BIM-511298
Modern Language Association (MLA)
Ceafalan, Laura Cristina…[et al.]. Cellular Players in Skeletal Muscle Regeneration. BioMed Research International No. 2014 (2014), pp.1-21.
https://search.emarefa.net/detail/BIM-511298
American Medical Association (AMA)
Ceafalan, Laura Cristina& Popescu, Bogdan Ovidiu& Hinescu, Mihail Eugen. Cellular Players in Skeletal Muscle Regeneration. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-21.
https://search.emarefa.net/detail/BIM-511298
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511298