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Oxidative Stress and Antioxidant Activity in Hypothermia and Rewarming : Can RONS Modulate the Beneficial Effects of Therapeutic Hypothermia?
Joint Authors
Palomeque, Jesús
Carbonell, Teresa
Alva, Norma
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-02
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Hypothermia is a condition in which core temperature drops below the level necessary to maintain bodily functions.
The decrease in temperature may disrupt some physiological systems of the body, including alterations in microcirculation and reduction of oxygen supply to tissues.
The lack of oxygen can induce the generation of reactive oxygen and nitrogen free radicals (RONS), followed by oxidative stress, and finally, apoptosis and/or necrosis.
Furthermore, since the hypothermia is inevitably followed by a rewarming process, we should also consider its effects.
Despite hypothermia and rewarming inducing injury, many benefits of hypothermia have been demonstrated when used to preserve brain, cardiac, hepatic, and intestinal function against ischemic injury.
This review gives an overview of the effects of hypothermia and rewarming on the oxidant/antioxidant balance and provides hypothesis for the role of reactive oxygen species in therapeutic hypothermia.
American Psychological Association (APA)
Alva, Norma& Palomeque, Jesús& Carbonell, Teresa. 2013. Oxidative Stress and Antioxidant Activity in Hypothermia and Rewarming : Can RONS Modulate the Beneficial Effects of Therapeutic Hypothermia?. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-511302
Modern Language Association (MLA)
Alva, Norma…[et al.]. Oxidative Stress and Antioxidant Activity in Hypothermia and Rewarming : Can RONS Modulate the Beneficial Effects of Therapeutic Hypothermia?. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-511302
American Medical Association (AMA)
Alva, Norma& Palomeque, Jesús& Carbonell, Teresa. Oxidative Stress and Antioxidant Activity in Hypothermia and Rewarming : Can RONS Modulate the Beneficial Effects of Therapeutic Hypothermia?. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-511302
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511302