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Positive Selection and the Evolution of izumo Genes in Mammals
Joint Authors
Source
International Journal of Evolutionary Biology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Most genes linked to male reproductive function have been known to evolve rapidly among species and to show signatures of positive selection.
Different male species-specific reproductive strategies have been proposed to underlie positive selection, such as sperm competitive advantage and control over females postmating physiology.
However, an underexplored aspect potentially affecting male reproductive gene evolution in mammals is the effect of gene duplications.
Here we analyze the molecular evolution of members of the izumo gene family in mammals, a family of four genes mostly expressed in the sperm with known and potential roles in sperm-egg fusion.
We confirm a previously reported bout of selection for izumo1 and establish that the bout of selection is restricted to the diversification of species of the superorder Laurasiatheria.
None of the izumo genes showed evidence of positive selection in Glires (Rodentia and Lagomorpha), and in the case of the non-testes-specific izumo4, rapid evolution was driven by relaxed selection.
We detected evidence of positive selection for izumo3 among Primates.
Interestingly, positively selected sites include several serine residues suggesting modifications in protein function and/or localization among Primates.
Our results suggest that positive selection is driven by aspects related to species-specific adaptations to fertilization rather than sexual selection.
American Psychological Association (APA)
Grayson, Phil& Civetta, Alberto. 2012. Positive Selection and the Evolution of izumo Genes in Mammals. International Journal of Evolutionary Biology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-511410
Modern Language Association (MLA)
Grayson, Phil& Civetta, Alberto. Positive Selection and the Evolution of izumo Genes in Mammals. International Journal of Evolutionary Biology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-511410
American Medical Association (AMA)
Grayson, Phil& Civetta, Alberto. Positive Selection and the Evolution of izumo Genes in Mammals. International Journal of Evolutionary Biology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-511410
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511410