![](/images/graphics-bg.png)
Inflammation in Cardiovascular Tissue Engineering : The Challenge to a Promise: A Minireview
Joint Authors
Schulte, Jason B.
Fercana, George
Simionescu, Dan T.
Simionescu, Agneta
Source
International Journal of Inflammation
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-09
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Tissue engineering employs scaffolds, cells, and stimuli brought together in such a way as to mimic the functional architecture of the target tissue or organ.
Exhilarating advances in tissue engineering and regenerative medicine allow us to envision in vitro creation or in vivo regeneration of cardiovascular tissues.
Such accomplishments have the potential to revolutionize medicine and greatly improve our standard of life.
However, enthusiasm has been hampered in recent years because of abnormal reactions at the implant-host interface, including cell proliferation, fibrosis, calcification and degeneration, as compared to the highly desired healing and remodeling.
Animal and clinical studies have highlighted uncontrolled chronic inflammation as the main cause of these processes.
In this minireview, we present three case studies highlighting the importance of inflammation in tissue engineering heart valves, vascular grafts, and myocardium and propose to focus on the endothelial barrier, the “final frontier” endowed with the natural potential and ability to regulate inflammatory signals.
American Psychological Association (APA)
Simionescu, Agneta& Schulte, Jason B.& Fercana, George& Simionescu, Dan T.. 2011. Inflammation in Cardiovascular Tissue Engineering : The Challenge to a Promise: A Minireview. International Journal of Inflammation،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-511422
Modern Language Association (MLA)
Simionescu, Agneta…[et al.]. Inflammation in Cardiovascular Tissue Engineering : The Challenge to a Promise: A Minireview. International Journal of Inflammation No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-511422
American Medical Association (AMA)
Simionescu, Agneta& Schulte, Jason B.& Fercana, George& Simionescu, Dan T.. Inflammation in Cardiovascular Tissue Engineering : The Challenge to a Promise: A Minireview. International Journal of Inflammation. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-511422
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511422