Lighting Up RNA-Cleaving DNAzymes for Biosensing
Joint Authors
Li, Yingfu
Tram, Kha
Kanda, Pushpinder
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The development of the in vitro selection technique has allowed the isolation of functional nucleic acids, including catalytic DNA molecules (DNAzymes), from random-sequence pools.
The first-ever catalytic DNA obtained by this technique in 1994 is a DNAzyme that cleaves RNA.
Since then, many other RNase-like DNAzymes have been reported from multiple in vitro selection studies.
The discovery of various RNase DNAzymes has in turn stimulated the exploration of these enzymatic species for innovative applications in many different areas of research, including therapeutics, biosensing, and DNA nanotechnology.
One particular research topic that has received considerable attention for the past decade is the development of RNase DNAzymes into fluorescent reporters for biosensing applications.
This paper provides a concise survey of the most significant achievements within this research topic.
American Psychological Association (APA)
Tram, Kha& Kanda, Pushpinder& Li, Yingfu. 2012. Lighting Up RNA-Cleaving DNAzymes for Biosensing. Journal of Nucleic Acids،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-511462
Modern Language Association (MLA)
Tram, Kha…[et al.]. Lighting Up RNA-Cleaving DNAzymes for Biosensing. Journal of Nucleic Acids No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-511462
American Medical Association (AMA)
Tram, Kha& Kanda, Pushpinder& Li, Yingfu. Lighting Up RNA-Cleaving DNAzymes for Biosensing. Journal of Nucleic Acids. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-511462
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511462