Interferon Beta-1a Improves Urinary Symptoms, Reduces Proviral Load, and Modifies the Immune Response in a Patient with HAMTSP
Joint Authors
Costa, Davi Tanajura
Santos, André Muniz
Santos, Silvane
Passos, Lúcia
Sundberg, Michael
Source
Case Reports in Neurological Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-16
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
The human T-cell lymphotropic virus type 1 (HTLV-1) is the known causative agent of a chronic neurologic condition known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Although several therapies have been evaluated for HAM/TSP, none have been approved for use in humans.
In this paper, we describe a 55-year-old female patient with HAM/TSP who was treated with interferon beta-1a.
This patient, in comparison to 20 female patients with HAM/TSP who were not treated, showed improvement in urinary symptoms over four years of therapy, as well as a reduction in HTLV-1 proviral load and serum cytokine levels typically observed in HAM/TSP.
This improved outcome merits further controlled studies on the use and efficacy of interferon beta-1a as a therapy for HAM/TSP.
American Psychological Association (APA)
Costa, Davi Tanajura& Sundberg, Michael& Passos, Lúcia& Santos, André Muniz& Santos, Silvane. 2012. Interferon Beta-1a Improves Urinary Symptoms, Reduces Proviral Load, and Modifies the Immune Response in a Patient with HAMTSP. Case Reports in Neurological Medicine،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-511471
Modern Language Association (MLA)
Costa, Davi Tanajura…[et al.]. Interferon Beta-1a Improves Urinary Symptoms, Reduces Proviral Load, and Modifies the Immune Response in a Patient with HAMTSP. Case Reports in Neurological Medicine No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-511471
American Medical Association (AMA)
Costa, Davi Tanajura& Sundberg, Michael& Passos, Lúcia& Santos, André Muniz& Santos, Silvane. Interferon Beta-1a Improves Urinary Symptoms, Reduces Proviral Load, and Modifies the Immune Response in a Patient with HAMTSP. Case Reports in Neurological Medicine. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-511471
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511471